Saturday, February 18, 2012

Methotrexate Injectable Shortage ~ Not just Preservative Free . . .

FDA Drug Shortage List
According to the update on the FDA's Drug Shortage List (updated on 2.16.12), it isn't just the preservative free that is in short supply.  Though the Preservative Free formula is in the shortest supply.

APP has discontinued production of their 2 mL vials of methotrexate (with preservative), thus leaving their 10 mL vials (with preservative; same concentration) in higher demand.  Hospira is continuing to make their 2 mL vials (25 mg/mL).  However, with the decrease in total quantity available, these are in short supply.  Hospira is expected to release more of the 2 mL vials before the end of the month.
Hospira's Customer Service line is: 1-877-946-7747
APP's Customer Service line is: 1-888-386-1300
They should be able to head you in the right direction, if your supply is running low.

Note: If you take more than 25 mg per week, you'd be better off trying to source the 10 mL vials.  Since they offer a total of 250mg of methotrexate per vial.  Since it contains preservative, there are multiple doses per vial.

Other drug shortages that may affect you:
The generic form of Zofran (Ondansetron) injectable and Volataren Gel are in short supply.

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